Foundry Integrative Psychiatry and Wellness, PLLC

When psychiatric symptoms have medical causes

Thyroid disease, sleep apnea, hormonal transitions, vitamin deficiencies, and everyday medications can each produce or worsen psychiatric symptoms. A good evaluation looks for them.

Editorial information

Published by Foundry Integrative Psychiatry and Wellness, PLLC. Updated 2026-10-25. Clinical review of this revision is pending; no clinician sign-off is claimed.

The numbers are larger than most people expect

Medical conditions contribute to depressive symptoms more often than many people expect. Sleep apnea alone affects roughly a third of people with major depression and is routinely missed, because its daytime symptoms — fatigue, poor concentration, irritability — look psychiatric.

Your medicine cabinet is part of the evaluation

More than 200 common prescription medications list depression as a possible side effect, and people taking several of them report depressive symptoms more often. Blood-pressure medications, steroids, hormonal agents, acid reducers, and others belong in the conversation — which is why Foundry asks for every medication and supplement, with doses.

What gets checked, and why history leads

Baseline labs are often checked for new presentations — thyroid function, blood counts, metabolic panel, B12 and folate — and a careful history and medication review often finds more than routine lab panels do. The long first conversation is the diagnostic instrument; labs confirm what it raises.

Safety and scope

This guide is general education, not medical advice. It does not create a treatment relationship, diagnose a condition, promise medication, or replace crisis care. For immediate danger use 911, 988, or the nearest emergency department.

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